Medications Explainedby a Pharmacist

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GLP-1s, Diabetes & Weight Management

3 reasons Jardiance may be prescribed

Aug 13, 2026 · Short · Empagliflozin

Jardiance isn't just a diabetes medication anymore.

Jardiance (empagliflozin) originally became well known as an SGLT2 inhibitor used to help lower blood sugar in people with type 2 diabetes.

But its role has expanded significantly.

Depending on the patient and indication, Jardiance may be prescribed for:

  • Type 2 diabetes
  • Heart failure
  • Chronic kidney disease

And here's the surprising part: some patients may receive Jardiance for its heart or kidney benefits even when lowering blood sugar isn't the primary reason they're taking it.

Jardiance works through the kidneys by blocking part of the glucose and sodium reabsorption process, but the effects of SGLT2 inhibition extend well beyond simply removing glucose through the urine.

Want to understand exactly how that works? Watch my full Jardiance Explained video for the mechanism, heart and kidney benefits, side effects, and important warnings.

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