GLP-1 weight-loss pills: common side effects

GLP-1 weight loss pills are getting a lot of attention—but what side effects should you actually expect?

In this video, I explain the common side effects of oral GLP-1 medications from a pharmacist's perspective, including why these medications can cause nausea, vomiting, diarrhea, constipation, stomach discomfort, decreased appetite, and other gastrointestinal symptoms.

You'll also learn why GLP-1 medications affect the digestive system, which side effects may improve as your body adjusts, and when symptoms deserve a conversation with your healthcare provider.

Whether you're researching an oral GLP-1 weight loss medication, already taking one, or comparing GLP-1 pills with injectable medications such as Ozempic, Wegovy, or Mounjaro, understanding the potential benefits and side effects can help you have a more informed conversation with your doctor or pharmacist.

• In this video:

Common GLP-1 side effects

Why nausea can happen

Diarrhea and constipation

Changes in appetite

Stomach and digestive symptoms

What may happen when increasing the dose

When side effects may require medical attention

Practical pharmacist counseling tips